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Faculty of Medicine教員紹介:徳嶺 譲芳

氏名
徳嶺 譲芳
トクミネ ジョウホウ TOKUMINE, Joho
職位教授
学内の役職・委員等CVC委員
所属教室

麻酔科学教室

専攻・専門分野(大学院)

医学専攻 麻酔科学分野(新課程)

外科系専攻 麻酔科学分野(旧課程)

担当科目(学部)麻酔科学
担当科目(大学院)「血管確保」
専門分野麻酔科学
研究テーマ安全な中心静脈穿刺手技と教育体制の構築
気道エコー
略歴1988年 琉球大学大学院 医学研究科 入学
1992年 同上 修了
2000年 カリフォルニア大学サンディエゴ校 留学
2002年 同上 帰国
2009年 日本臨床麻酔学会誌賞 受賞
2013年 日本麻酔学会第59回学術集会 最優秀演題賞 受賞
所有する学位博士(医学)
指導医・専門医・認定医、その他の資格等麻酔指導医
麻酔科標榜医
論文・著書等を含む主要研究業績 1. Tokumine J, Yorozu T, Moriyama K, Suzuki T, Okada C. Outcome-based simulation training for ultrasound-guided central venous catheter placement: clinical impact on preventing mechanical complications. BMC Med Educ. 2025;25(1):131.
2. Watanabe H, Nakazawa H, Tokumine J, Yorozu T. Real-time vs. static ultrasound-guided needle cricothyroidotomy: a randomized crossover simulation trial. Sci Rep. 2025;15(1):8112.
3. Tokumine J, Moriyama K, Yorozu T. Variation in the amount of leakage containing inhalational anaesthetics in the breathing circuits of anaesthesia machines (Correspondence). Anaesthesia. 2024;79(9):1003-1004.
4. Tokumine J, Moriyama K, Yorozu T. Clues for diagnosing misplaced central venous catheter in the right ascending lumbar vein during right femoral venous access. World J Clin Cases. 2024; 12(24):5473-5475.
5. Saito Y, Takeuchi H1, Tokumine J, Sawada R, Watanabe K, Yorozu T (1. Department of Surgery) Ultrasound-guided peripheral nerve blocks for anteriorcutaneous nerve entrapment syndrome after robot-assisted gastrectomy: A case report. World J Gastrointest Surg 2024;16(8): 2719-2723.
6. Watanabe K, Tokumine J, Nagase M, Sawada R, Kinjo S, Yorozu T. A new and simplified extraoral approach for inferior alveolar nerve block: a cadaveric study and clinical case reports. J Anesth 2024;38(6):806-810.
7. Motoyama H, Tokumine J, Saito Y, Moriyama K, Yorozu T. Ultrasound-guided radial vein cannulation for general anesthesia in cases with difficult peripheral venous access: a report of two cases. JA Clinical Reports. 2024;10:58
8. Tokumine J, Moriyama K, Yorozu T. Influence of Arm Abduction on Ipsilateral Internal Jugular Vein Misplacement During Ultrasound-Guided Subclavian Venous Catheterization. Crit Care Med. 2024; 52(12):e646-e647, DOI: 10.1097/CCM.0000000000006410
9. TokumineJ, Fujimaki K, Moriyama K, Yorozu T. Workflow for treating inadvertent arterial placement of the central venous catheter. J Geriatr Cardiol 2024;21(11):1096-1098.
10. Takeuchi N, Koshihara M, Motoyasu A, Tokumine J, Nakazawa H, Ozaki M, Yorozu T. General anesthesia for cesarean section in a pregnant woman with systemic vascular malformation: a case report. JA Clin Rep. 2023;9(1):88.
11. Nakazawa H, Uzawa K, Tokumine J, Lefor AK, Motoyasu A, Yorozu T. Airway ultrasound for patients anticipated to have a difficult airway: Perspective for personalized medicine. World J Clin Cases. 2023;11(9):1951-1962.
12. Tokumine J, Nakazawa H, Morimoto Y, Yorozu T. Do not misidentify a venous valve as a venous dissection. Radiol Case Rep. 2023;18(4):1403-1405.
13. Kohyama T, Fujimaki K, Sasamori H, Tokumine J, Moriyama K, Yorozu T. Inadvertent catheter misplacement into the subclavian artery during ultrasound-guided internal jugular venous catheterization: a case report. JA Clin Rep. 2023;9(1):58.
14. Sekiguchi S, Moriyama K, Tokumine J, Lefor AK, Nakazawa H, Tomita Y, Yorozu T. Near-infrared venous imaging may be more useful than ultrasound guidance for novices to obtain difficult peripheral venous access: A crossover simulation study. Medicine (Baltimore). 2023;102(12):e33320.
15. Wada N, Furutani A, Tokumine J, Nakazawa H, Shimazu K, Yorozu T. Ultrasound-Guided Glossopharyngeal Nerve Block for an Awake Intubation in a Patient Predicted to Have a Difficult Airway: A Case Report. A A Pract. 2023;17(5):e01682.
16. Moriyama K, Koh M, Takeuchi N, Tokumine J, Yorozu T Aberrant cessation of inhalation anesthesia in an anesthesia machine equipped with a digital vaporizer. Can J Anaesth. 2023;70(8):1414-1415.
17. Harumasa Nakazawa, Joho Tokumine, Alan Lefor, Katsuya Yamamoto, Hiroyuki Karasawa, Keisuke Shimazu, Tomoko Yorozu. Use of a photoacoustic needle improves needle tip recognition in a video recording of simulated ultrasound-guided vascular access: a pilot study. J Vasc Access, 2022:11297298221122137.
18. Sugiki D, Matsushima H, Asao T, Tokumine J, Lefor AK, Kamisasanuki T, Suzuki M, Gomei S. A web-based self-learning system for ultrasound-guided vascular access. Medicine (Baltimore) 2022;101:43(e31292).
19. Moriyama K, Ando T, Kotani M, Tokumine J, Nakazawa H, Motoyasu A, Yorozu T. Risk factors associated with increased incidences of catheter-related bloodstream infection. Medicine (Baltimore) 2022;101(42): e31160 .
20. Sawada R, Watanabe K, Tokumine J, Lefor AK, Ando T, Yorozu T. Ultrasound-guided rectus sheath block for anterior cutaneous nerve entrapment syndrome after laparoscopic surgery: A case report. World J Clin Cases. 2022;10(7):2357-2362.
21. Noguchi H, Seki H, Tokumine J, Nakazawa H, Yorozu T. Bleeding After Central Venous Catheter Placement in a Patient With Undiagnosed Acquired Hemophilia A: A Case Report. Cureus. 2022;14(7):e27444.
22. Nagase M, Nagase T, Tokumine J, Saito K, Sunami E, Shiokawa Y, Matsumura G. Formalin-free soft embalming of human cadavers using N-vinyl-2-pyrrolidone: perspectives for cadaver surgical training and medical device development. Anat Sci Int. 2022.
23. Kikuchi M, Asao T, Tokumine J, Lefor AK, Matsushima H, Andoh H, Tanaka K, Kanamoto M, Ideno Y. A novel system for teaching the in-plane vascular access technique: A simulation study. Medicine (Baltimore). 2021;100(37):e27201.
24. Okano H, Mayumi T, Kataoka Y, Banno M, Tsujimoto Y, Shiroshita A, Taito S, Tokumine J. Outcomes of Simulation-Based Education for Vascular Access: A Systematic Review and Meta-Analysis. Cureus 2021;13(8):e17188.
25. Watanabe K, Tokumine J, Lefor AK, Nakazawa H, Yamamoto K, Karasawa H, Nagase M, Yorozu T. Photoacoustic needle improves needle tip visibility during deep peripheral nerve block. Sci Rep. 2021;11(1):8432.
26. Tokumine J, Watanabe H, Moriyama K, Tabuchi S, Motoyasu A, Kageyama E, Yorozu T. In Response: " Massive leak in CO2 absorber of Perseus A500 did not inhibit mechanical ventilation but manual bag ventilation: A case report with experimental reproduction." A A Pract. 2021;15(7):e01498.
27. Watanabe H, Moriyama K, Tokumine J, Tabuchi S, Motoyasu A, Kageyama E, Yorozu T. Massive leak in CO2 absorber of Perseus A500 did not inhibit mechanical ventilation but manual bag ventilation: A case report with experimental reproduction. A A Pract. 2021;15(3):e01425.
28. Tsuji D, Okano H, Tokumine J, Lefor AK, Ema S, Yorozu T. Midline catheter placement in an obese patient with difficult venous access. Med Case Rep Study Protoc. 2020;1:1(e0009).
29. Watanabe K, Tokumine J, Lefor AK, Yorozu T. Shallow-angle needle guide for ultrasound-guided internal jugular venous catheterization: A randomized controlled crossover simulation study (CONSORT). PLoS One. 2020 Jun 30;15(6):e0235519.
30. Katayama A, Watanabe K, Tokumine J, Lefor AK, Nakazawa H, Jimbo I, Yorozu T. Cricothyroidotomy needle length is associated with posterior tracheal wall injury: A randomized crossover simulation study (CONSORT). Medicine (Baltimore). 2020 Feb;99(9):e19331.
31. Watanabe K, Tokumine J, Lefor AK, Moriyama K, Yorozu T. Ultrasound-guided hydrodissection of an entrapped saphenous nerve after lower extremity varicose vein stripping: A case report. A A Pract. 2019 Nov 19. doi: 10.1213/XAA.0000000000001143.
32. Safety Committee of Japanese Society of Anesthesiologists. Practical guide for safe central venous catheterization and management 2017. [Working Group for Safe Central Venous Catheterization and Management: Nishiwaki K, Kawamoto M, Shibata Y, Takeuchi M, Tanaka K, and Tokumine J], J Anesth. 2019 Nov 30. doi: 10.1007/s00540-019-02702-9. [Epub ahead of print] Review.
33. Jimbo I, Uzawa K, Tokumine J, Mitsuda S, Watanabe K, Yorozu T. Ultrasonographic identification of the cricothyroid membrane in a patient with a difficult airway as a result of cervical hematoma caused by hemophilia: a case report. BMC Anesthesiol. 2019;19(1):124.
34. Asao T, Kikuchi M, Tokumine J, Matsushima H, Andoh H, Tanaka K, Kanamoto M, Ideno Y. Optical skill-assist device for ultrasound-guided vascular access: A preliminary simulation study. Medicine (Baltimore). 2019 Jun;98(26):e16126.
35. Watanabe K, Moriyama K, Tokumine J, Yorozu T. Effect of hangebyakujutsutemmato on pregabalin-induced dizziness in a rat model of neuropathic pain, Traditional & Kampo Medicine, 10 May 2019. https://doi.org/10.1002/tkm2.1218
36. Saijo F, Mutoh M, Tokumine J, Yoshinobu O, Hama H, Namima T, Shibahara M, Tokumura H: Late fracture of Groshong ports: A report of the three cases. J Vasc Access. 129729819834512, 2019.
37. Katayama A, Nakazawa H, Tokumine J, Lefor AK, Watanabe K, Asao T, Yorozu T: A high-fidelity simulator for needle cricothyroidotomy training is not associated with increased proficiency compared with conventional simulators: A randomized controlled study. Medicine (Baltimore). 98(8):e14665, 2019.
38. Mitsuda S, Tokumine J, Matsuda R, Yorozu T, Asao T: PICC insertion in the sitting position for a patient with congestive heart failure: A case report. Medicine (Baltimore). 2019;98(6):e14413.
39. Yokota T, Tokumine J, Lefor AK, Hasegawa A, Yorozu T, Asao T: Ultrasound-guided placement of a midline catheter in a patient with extensive postburn contractures: A Case report. Medicine (Baltimore). 2019;98(3):e14208.
40. Wada N, Tashima K, Motoyasu A, Nakazawa H, Tokumine J, Chinzei M, Yorozu T: Anesthesia for patient with anti-N-methyl-D-aspartate receptor encephalitis: A case report with a brief review of the literature. Medicine (Baltimore). 97(50):e13651,2018.
41. Watanabe K, Tokumine J, Lefor AK1, Motoyasu A, Moriyama K, Yorozu T (1Jichi Medical University): A Shallow Angle Short-Axis Out-of-Plane Approach Reduces the Rate of Posterior Wall Injuries in Central Venous Catheterization: A Simulation Study. Biomed Res Int. eCollection 2018:4793174, 2018.
42. Okano H, Uzawa K, Watanabe K, Motoyasu A, Tokumine J, Lefor AK, Yorozu T : Ultrasound-guided identification of the cricothyroid membrane in a patient with a difficult airway: a case report. BMC Emerg Med. 18(1):5, 2018.
43. Mitsuda S, Motoyasu A, Tokumine J, Watanabe K, Morimoto Y, Yorozu T: Atypical Venous Valve of the Internal Jugular Vein. J Cardiothorac Vasc Anesth. 32(1):e30-e31, 2018.
44. Watanabe K, Mitsuda S, Motoyasu A, Tokumine J, Moriyama K, Yorozu T. Iatrogenic carpal tunnel syndrome induced by wrist extension for placement of an indwelling radial artery catheter: a case report. JA Clin Rep. 3(1):51, 2017.
45. Watanabe K, Tokumine J, Lefor AK, Moriyama K, Sakamoto H, Inoue T, Yorozu T: Postoperative analgesia comparing levobupivacaine and ropivacaine for brachial plexus block: A randomized prospective trial. Medicine (Baltimore). 2017;96(12):e6457.
46. Watanabe K, Tokumine J, Yorozu T, Moriyama K, Sakamoto H, Inoue T. Particulate-steroid betamethasone added to ropivacaine in interscalene brachial plexus block for arthroscopic rotator cuff repair improves postoperative analgesia. BMC Anesthesiol. 2016;16(1):84.
47. Watanabe K, Mitsuda S, Tokumine J, Lefor AK, Moriyama K, Yorozu T. Quadratus lumborum block for femoral-femoral bypass graft placement: A case report. Medicine (Baltimore). 2016;95(35):e4437.
48. Uzawa K, Tokumine J, Lefor AK, Takagi T, Watanabe K, Yorozu T: Difficult Airway Due to an Undiagnosed Subglottic Tumor: A Case Report. Medicine (Baltimore). 2016;95(15):e3383.
49. Kawagishi K, Tokumine J, Lefor AK: The relationship of the subclavius muscle with relevance to venous cannulation below the clavicle. Anesthesiol Res Pract. 2016:6249483,2016.
50. Hirai E, Tokumine J, Lefor AK, Ogura S, Kawamata M: Bladder explosion during transurethral resection of the prostate with nitrous oxide inhalation. Case Rep Anesthesiol. 2015:464562,2015.
51. Morimoto Y, Shimamoto Y, Tanaka E, Tokumine J: Images in Anesthesiology: Detection of large inferior thyroid Artery by ultrasound prescan before internal jugular vein catheterization. Anesthesiology 123(4):927,2015.
52. Tokumine J, Matsushima H, Lefor AK, Igarashi H, Ono K: Ultrasound-guided subclavian venipuncture is more rapidly learned than the anatomic landmark technique in simulation training. J Vasc Access.16(2):144-147,2015.
53. Morimoto Y, Tanaka E, Shimamoto Y, Tokumine J: Dissection of the posterior wall by guide-wire during internal jugular vein catheterization. J Anesth 29(2):289-291,2015.
54. Tokumine J, Lefor AK, Yasutani T, Sekiguchi T, Motoyasu A, Yorozu T: Abduction of the ipsilateral upper arm straightens the axillary vein. Int Arch Clin Anesth Res. 2015;1:23-24.
55. Tadokoro T, Tokumine J, Lefor AT, Kawabata T, Yoza K, Kinjo T. The three-step method for ultrasound-guided pediatric internal jugular venous catheterization: a clinical trial. J Anesth. 2015;29(1):131-3.
56. Tokumine J, Lefor AT, Yonei A, Kagaya A, Iwasaki K, Fukuda Y: Three-step method for ultrasound-guided central vein catheterization. Br J Anaesth. 110:368-73,2013.
57. Tomoyose T, Ohama M, Yamanoha A, Masuzaki H, Okudaira T, Tokumine J: Real-time ultrasound-guided central venous catheterization reduces the need for prophylactic platelet transfusion in thrombocytopenic patients with hematological malignancy. Transfus Apher Sci. 49:367-9,2013.
58. Tokumine J, Lefor AT, Morimoto Y, Sanuki M, Asai T, Ohde S: A novel cannula-over-needle system for ultrasound-guided central venous catheterization. J Anesth.26:941-2,2012.
59. Tokumine J, Sugahara K, Nitta K, Fuchigami T, Abe M, Gushiken K, Oda M, Okayama H: Aberrant halt of syringe pump motion: an improved system to prevent false setting of the syringe. J Anesth. 20:118-21,2006.
60. Tokumine J, Sugahara K, Gushiken K, Ohta M, Matsuyama T, Saikawa S: Non-zero basal oxygen flow a hazard to anesthesia breathing circuit leak test. Anesth Analg. 100:1056-8,2005.
61. Kinjo S, Tokumine J, Sugahara K, Kakinohana M, Iha K, Matsuda H, Akasaki M, Yamashiro S: Unexpected hemodynamic deterioration and mitral regurgitation due to a tissue stabilizer during left anterior descending coronary anastomosis in off-pump coronary artery bypass graft surgery. Ann Thorac Cardiovasc Surg. 11:324-8,2005.
62. Tokumine J, Sugahara K, Fuchigami T, Teruya K, Nitta K, Satou K: Unanticipated full stomach at anesthesia induction in a type I diabetic patient with asymptomatic gastroparesis. J Anesth. 2005;19:247-248.
63. Tokumine J, Sugahara K, Matsuyama T, Nitta K, Fuchigami T, Miyaguni T: Shaw scalpel for breast mastectomy in a pacemaker-implanted patient. J Anesth. 2005;19:349.
64. Koja H, Tokumine J, Sugahara K, Yamashiro S, Uezu T, Koja K: Subcutaneous pulsating neck mass after left internal jugular venipuncture. J Cardiothorac Vasc Anesth. 2004;18:806-808.
65. Kawabata T, Tokumine J, Nakamura S, Sugahara K: Unanticipated vomiting and pulmonary aspiration at anesthesia induction in a formula-fed 4-month-old infant. Anesthesiology. 2004;100:1330-1331.
66. Kakinohana M, Tokumine J, Kawashima S, Koja H, Sugahara K: Patient-controlled sedation using propofol in eight patients with endstage renal failure. J Anesth. 2004;18:39-42.
67. Tokumine J, Sugahara K, Ura M, Takara I, Oshiro M, Owa T: Lingual tonsil hypertrophy with difficult airway and uncontrollable bleeding. Anaesthesia. 2003;58:390-391.
68. Tokumine J, Kakinohana O, Cizkova D, Smith DW, Marsala M: Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat. J Neurosci Res. 2003;74:552-561.
69. Tokumine J, Sugahara K, Tomori T, Nagasawa Y, Takaesu Y, Hokama: A. Tissue necrosis caused by extravasated propofol. J Anesth. 2002;16:358-359.
70. Tokumine J, Iha H, Okuda Y, Shimabukuro T, Shimabukuro T, Ishigaki K, Nakamura S, Takara I: Appropriate method of administration of propofol, fentanyl, and ketamine for patient-controlled sedation and analgesia during extracorporeal shock-wave lithotripsy. J Anesth. 200;14:68-72.
71. Tokumine J, Iha H, Okuda Y, Ishigaki K, Oshiro M, Nakamura S, Fuchibe M, Teruya K: Gastric tube guide-equipped laryngeal mask airway. J Anesth. 2000;14:221-223.
72. Tokumine J, Iha H, Okuda Y, Nitta K, Ishigaki K, Oshiro M, Shimabukuro T: A comparison between low-flow leak test and oxygen flush leak test. J Anesth. 2000;14:191-193.
所属学会 日本麻酔科学会
日本臨床麻酔学会(学会誌査読委員)
日本医学シミュレーション学会(理事)
医療の質・安全学会(代議員)
公的な委員会等の役員・委員歴一般社団法人 医療安全全国共同行動「行動目標3b」中心静脈穿刺 支援部会委員長
公益社団法人 日本麻酔科学会 中心静脈カテーテル挿入の手引き改訂ワーキング・グループ委員
学外活動Medicine (Baltimore): Academic Editor
BioMed Research International: Academic Editor
The Journal of International Medical Research: Editorial Board Member
Clinical Medicine Insights: Case Reports: Editorial Board Member
Current Cardiology Review: Executive Guest Editor
学生のみなさんへ生きるって、ベクトルみたいなものなんだ。

人生には、楽しいこともつらいこともある。
自分のせいでうまくいかないときもあれば、理不尽に傷つくこともある。
でも、生きるっていうのは、そういう毎日のいろんな出来事に向き合いながら、
「自分はこっちに進みたい」って思う方向に向かって、精一杯進むことなんだと思う。
周りの人は、君のことを「成功した」「失敗した」って判断するかもしれない。
だけど、最後に大事なのは、「自分はどこを目指して生きてきたか」ってこと。
その答えの中に、「自分って何者だったか」が見えてくるんじゃないかな。
関連サイト エコーガイド下中心静脈穿刺
電子メール jtokumine@ks.kyorin-u.ac.jp