教員紹介：村田 光繁
| 氏名 |
村田 光繁
ムラタ ミツシゲ MURATA, Mitsushige |
|---|---|
| 職位 | 教授 |
| 所属教室 | |
| 専攻・専門分野 （大学院） |
医学専攻 循環器内科学分野（新課程）
|
| 担当科目（学部） | 循環器内科学 |
| 専門分野 | 循環器内科学、特に弁膜症、心筋症、心不全、肺高血圧症など |
| 研究テーマ | 心筋スペックルトラッキング法や３次元心エコー法を用いた心機能解析。特に右室機能解析を中心とした研究を実施し、心疾患における右室機能の重要性を世界に発信しています。 |
| 略歴 | 1995年 慶應義塾大学医学部卒業 1999年 慶應義塾大学大学院医学研究科博士課程修了 1999年 浦和市立病院（現さいたま市立病院）勤務 2000年 米国ジョーンズホプキンス大学留学 2004年 慶應義塾大学医学部助手 2008年 慶應義塾大学病院中央臨床検査部専任講師 2019年 東海大学医学部臨床検査学教授（付属八王子病院） 2025年 杏林大学医学部循環器内科学教授 |
| 所有する学位 | 博士（医学） |
| 指導医・専門医・認定医、その他の資格等 | 日本内科学会総合内科専門医・指導医 日本循環器学会専門医 日本超音波医学会専門医・指導医 日本心エコー図学会心エコー図専門医 日本心エコー図学会SHD認証医 日本臨床検査専門医・管理医 日本医師会認定産業医 |
| 論文・著書等を含む主要研究業績 |
Ohte N, Kikuchi S, Iwahashi N, Kinugasa Y, Dohi K, Takase H, Masai K, Inoue K, Okumura T, Hachiya K, Kitada S, Seo Y; EASY HFpEF Investigators: Distinctive left ventricular-arterial and right ventricular-pulmonary arterial coupling in patients with heart failure and a higher left ventricular ejection fraction range. Eur Heart J Cardiovasc Imaging 25: 774-781, 2024. (IF=6.3) Kimura M, Kohono T, Shinya Y, Hiraide T, Moriyama H, Endo J, Murata M, Fukuda K: De-escalation of oxygen-therapy and medication in patients with chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty. Can J Cardiol 39: 637-645, 2023 (IF=7.215) Ohte N, Kikuchi S, Iwahashi N, Kinugasa Y, Dohi K, Takase H, Masai K, Inoue K, Okumura T, Hachiya K, Kitada S, Seo Y; EASY HFpEF Investigators: Unfavorable outcomes in patients with heart failure with higher preserved left ventricular ejection frfaction. Eur Heart J Cardiovasc Imaging 24:293-300, 2022 (IF=6.3) Iwataki M, Murata M (corresponding authorship), Fujita M, Toide H, Akasaka K, Iino T, Goda A, Takei K, Toh N, Miyasaka Y, Yamano M, Ishizu T, Nakatani S, Yamamoto K: Survey results: status report on problems caused by sexual mismatch between sonographer and patient during echocardiography-a 2020 report of the Japanese Society of Echocardiography. J Echocardiogr 21:74-78, 2022 (IF=1.6) Kawakami T, Matsubara H, Shinke T, Abe K, Kohsaka S, Hosokawa K, Taniguchi Y, Shimokawahara H, Yamada Y, Kataoka M, Ogawa A, Murata M, Jinzaki M, Hirata K, Tsutsui H, Sato Y, Fukuda K: Efficacy and safety of balloon pulmonary angioplasty versis riociguat in inoperable chronic thromboembolic pulmonary hypertension: The MR BPA randomized controlled trial. The Lancet Respiratory Medicine 10: 949-960, 2022. (IF= 76.21) Murata M (corresponding authorship): Clinical Significance of Right Ventricular Function in Pulmonary Hypertension. Keio J Med 70: 60-67, 2021. Murata M (corresponding authorship), Kawakami T, Kataoka M, Moriyama H, Hiraide T, Kimura M, Endo J, Kohno T, Itabashi Y, Fukuda K: Clinical significance of guanylate cyclase stimulator, riociguat on right ventricular functional improvement in patients with pulmonary hypertension. Cardiology 146: 130-136, 2021. (IF=1.851) Kitakata H, Itabashi Y, Kanazawa H, Miura K, Kimura M, Shinada K, de Jongh MC, Endo J, Tsuruta H, Murata M, Kawamura A, Murata M, Fukuda K: Appropriate device selection for transcatheter atrial septal defect closure using three-dimensional transesophageal echocardiography. Int J Cardiovasc Imaging 37: 1159-1168, 2021. (IF=2.1) Tsugu T, Kawakami T, Kataoka M, Endo J, Kohno T, Itabashiu Y, Fukuda K, Murata M (corresponding authorship): Preoperative right ventricular strain predicts sustained right ventricular dysfunction after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension. Echocardiography 37: 2040-2047, 2020. (IF=1.5) Moriyama H, Kawakami T, Kataoka M, Hiraide T, Kimura M, Endo J, Kohno T, Itabashi Y, Seo Y, Fukuda K, Murata M (corresponding authorship): Regional right ventricular abnormalities implicate distinct pathophysiological conditions in patients with chronic thromboembolic pulmonary hypertension. J Am Heart Assoc 9: e018096, 2020. (IF=5.393) Tsugu T, Nagatomo Y, Muarta M, Iwanaga S: Giant papillary fibroelastoma attached to the left atrial septum, near the foramen ovale. Texas Heart Inst J 47:175-176, 2020. Nakayama S, Chubachi S, Sakurai K, Irie H, Tsutsumi A, Hashiguchi M, Itabashi Y, Murata M, Nakamura H, Asano K, Fukunaga K: Characteristics of chronic obstructive pulmonary disease patients with pulmonary hypertension assessed by echocardiography in a three-year observational cohort study. Int J Chron Obstruct Dis 15: 487-499, 2020. (IF= 2.808) Murata M (corresponding authorship), Kawakami T, Kataoka M, Kohno T, Itabashi Y, Fukuda K: Riociguat, a soluble guanylate cyclase stimulator ameliorates right ventricular strain assessed by two-dimensional speckle tracking echocardiography. Pulm Circ 8:2045893217746111, 2018. (IF= 2.58) Murata M (corresponding authorship), Tsugu T, Kawakami T, Kataoka M, Minakata Y, Endo J, Tsuruta H, Itabashi Y, Maekawa Y, Fukuda K: Speckle tracking analysis for the assessment of right ventricular dyssynchrony in patients with pulmonary arterial hypertension. Int J Cardiol 228:912-918, 2016. (IF= 3.5) Murata M (corresponding authorship), Tsugu T, Kawakami T, Kataoka M, Minakata Y, Endo J, Tsuruta H, Itabashi Y, Maekawa Y, Fukuda K: Prognostic value of three-dimensional echocardiographic right ventricular ejection fraction in patients with pulmonary arterial hypertension. Oncotarget 7:86781-86790, 2016. (IF= 5.168) Tohyama S, Hattori F, Sano M, Hishiki T, Nagahata Y, Matsuura T, Hashimoto H, Suzuki T, Yamashita H, Satoh Y, Egashira T, Seki T, Muraoka N, Yamakawa H, Ohgino Y, Tanaka T, Yoichi M, Yuasa S, Murata M, Suematsu M, Fukuda K: Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell. 12: 127-137, 2013. (IF= 23.9) Morikawa T, Murata M, Okuda S, Matsushita K, Iwanaga S, Murata M, Satoh T, Ogawa S, Fukuda K: Quantitative analysis of right ventricular function in patients with pulmonary hypertension using three-dimensional echocardiography and a two-dimensional summation method. Am J Cardiol. 107: 484-489, 2011. Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia CP, Keene AC, Alayari KN, Yamakawa H, Elling U, Berger C, Novatchkova M, Koglgruber R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai Y, Pfeufer A, Hicks AA, Pramstaller PP, Subramaniam S, Kimura A, Ocorr K, Bodmer R, Penninger JM: A novel in vivo Drosophia RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell 106: 142-153, 2010. (IF= 65.54) Hattori F, Chen H, Yamashita H, Tohyama S, Satoh Y, Yuasa S, Li W, Yamakawa H, Tanaka T, Onitsuka T, Shimoji K, Ohno Y, Egashira T, Kaneda R, Murata M, Hidaka K, Morisaki T, Sasaki E, Suzuki T, Sano M, Makino S, Oikawa S, Fukuda K: A non-genetic method for purifying stem cell-derived cardiomyocytes. Nature Methods 7: 61-66, 2010. (IF= 47.96) Murata M (corresponding authorship), Iwanaga S, Tamura Y, Kondo M, Kouyama K, Murata M, Ogawa S: A real-time 3-dimensional echocardiographic quantitative analysis of left atrial function in left ventricular diastolic dysfunction. Am J Cardiol. 102: 1097-1102, 2008. Yada H, Murata M (corresponding authorship) Shimoda K, Yuasa S, Kawaguchi H, Ieda M, Adachi T, Murata M, Ogawa S, Fukuda K: Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart. Circ Res 101: 69-77, 2007. Murata M, Cingolani E, McDonald AD, Donahue JK, Marbán E: Creation of a genetic calcium channel blocker by targeted Gem gene transfer in the heart. Circ Res 95: 398-405, 2004. Sasaki N, Murata M (shared first authorship), Guo Y, Jo SH, Ohler A, Akao M, O'Rourke B, Xiao RP, Bolli R, Marbán E: MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning. Circulation 107:1183-1188, 2003. (IF= 37.81) Murata M, Akao M, O'Rourke B, Marbán E: Mitochondrial ATP-sensitive potassium channels attenuate matrix Ca2+ overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection. Circ Res 89:891-898, 2001. |
| 所属学会 |
日本内科学会、日本循環器学会、日本心エコー図学会、日本超音波医学会、日本心臓病学会、日本肺高血圧肺循環学会、日本不整脈心電学会、日本心不全学会、日本心臓血管麻酔学会、日本臨床検査医学会、日本臨床検査専門医会、日本人間ドック学会、International Society for Heart Research (ISHR) |
医学部