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Graduate School of Medicine教員紹介：齊藤 邦昭
| 氏名 |
サイトウ クニアキ SAITO, Kuniaki |
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|---|---|---|
| 職位 | 講師 | |
| 学内の役職・委員等 | 病棟医長 | |
| 所属教室 | ||
| 専門分野 | 脳神経外科学(悪性脳腫瘍) | |
| 研究テーマ | ・グリオーマのジェネティクス、エピジェネティクス ・トラクトグラフィによる白質線維の描出と脳腫瘍手術への応用 | |
| 略歴 | 2002年：東京医科歯科大学卒業 2002年4月：東京大学病院脳神経外科研修医 2002年11月：埼玉医科大学総合医療センター研修医 2003年7月：寺岡記念病院脳神経外科 2003年12月：公立昭和病院脳神経外科 2006年3月：都立駒込病院脳神経外科 2008年11月：東京大学病院脳神経外科 2014年4月：杏林大学脳神経外科 | |
| 所有する学位 | 学士（医学） | |
| 指導医・専門医・認定医、その他の資格等 | 日本脳神経外科学会専門医 日本がん治療認定医機構日本がん治療認定医 日本神経内視鏡学会技術認定医 | |
| 論文・著書等を含む主要研究業績 |
論文： 1. Comparing artificial intelligence and physician performance in predicting IDH mutation status in glioma. Takahashi S, Takahashi M, Kinoshita M, Miyake M, Kawaguchi R, Shinojima N, Mukasa A, Saito K, Nagane M, Otani R, Higuchi F, Tanaka S, Hata N, Tamura K, Tateishi K, Nishikawa R, Arita H, Nonaka M, Uda T, Fukai J, Okita Y, Tsuyuguchi N, Kanemura Y, Tsushima F, Kakeda S, Akashi T, Taoka T, Watanabe Y, Yamada K, Hirai T, Azuma M, Yoshiura T, Sese J, Ichimura K, Narita Y, Hamamoto R. NPJ Digit Med. 2026 May 5. doi: 10.1038/s41746-026-02695-2. 2. Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup-specific prognostic stratification using economical/accessible diagnostic methods. Go K, Katsuma A, Yoshioka E, Shofuda T, Fukuoka K, Ichimura K, Matsushita Y, Mineharu Y, Makino Y, Kawauchi T, Sasaki A, Hirato J, Inoue T, Kodama Y, Mano M, Kanematsu D, Kijima N, Kagawa N, Keino D, Mukasa A, Suzuki T, Yoshimoto K, Kuga D, Horiguchi K, Yamaguchi S, Kanamori M, Yamasaki K, Ishibashi K, Akai T, Yamaoka M, Ishizaki R, Kawamura A, Ohba S, Ishida J, Ando R, Fukai J, Miwa T, Fujii M, Muroi A, Saito K, Harada A, Hayashi Y, Nonaka M, Park YS, Kobayashi Y, Higuchi T, Miyairi Y, Yoshifuji K, Takebe N, Oya S, Nakajo K, Nakada M, Nakano Y, Kambara M, Adachi K, Tanaka K, Nakamura H, Sonoda Y, Saito R, Wataya T, Kurozumi K, Taylor MD, Narita Y, Shibui S, Arai H, Sakamoto H, Date I, Nagane M, Nishikawa R, Arakawa Y, Kanemura Y. Brain Pathol. 2026 Mar 11:e70092. doi: 10.1111/bpa.70092. 3. グリオーマ手術における外視鏡を用いた5-ALA術中蛍光診断の有用性. 齊藤邦昭、佐々木重嘉、小林啓一、永根基雄、田中洋次. 日本レーザー医学会誌2026 年47 巻1 号 p. 97-103. doi: https://doi.org/10.2530/jslsm.jslsm-47_0006 4. 齊藤邦昭（分担執筆）: ナビゲーション①ステルスステーション. 大宅宗一監修. 遠藤英徳編集. 脳神経外科の手術器具＆機器 UP-TO-DATE. メディカ出版, 2025, 186-191. 5. Ikeda K，Saito K，Sasaki N，Kobayashi K，Nagane M：Aspiration prevention surgeries for adult brainstem malignant gliomas: illustrative cases．J Neurosurg Case Lessons. 2025; 10(14): CASE25284． 6. Ikeda K, Maruyama K, Kagiwata H, Yamamichi A, Okada K, Fujii S, Saito K, Nakatomi H, Hirano T, Nagane M: Posterior reversible encephalopathy syndrome arising from simultaneous cranioplasty and ventriculoperitoneal shunting: a case report. NMC Case Rep J 2025; 12: 323-329. 7. Nikai Y, Satomi K, Saito K, Gomyo M, Matsushita Y, Kato K, Nagahama K, Isomura A, Hayashi A, Yamagishi Y, Sasaki N, Kobayashi K, Tsuchiya K, Nagane M, Ichimura K, Shibahara J: Glioblastoma, IDH-wildtype manifesting as intracranial hemorrhage: A case report highlighting the clinical utility of digital polymerase chain reaction in integrated diagnoses. Neuropathology. 2025 Aug;45(4):e13025. 8. Sakamoto H, Tashiro S, Takebayashi M, Matsuda K, Saito K, Kobayashi K, Nagane M, Shiokawa Y, Nakatomi H, Yamada S : Could video game-based physical rehabilitation substitute for conventional physiotherapy in patients with glioma? A proof-of-concept study. Support Care Cancer. 2024 Dec 23;33(1):52. doi: 10.1007/s00520-024-09111-z. 9. Kanamori M, Tsuzuki S, Shibahara I, Saito K, Shimoda Y, Tanaka K, Yamaguchi S, Natsumeda M, Matsutani T, Hanihara M, Nakada M, Kuroda JI, Matsuda M, Yoshimoto K, Yonezawa U, Sonoda Y, Takano K, Yonezawa H, Otani Y, Nakahara Y, Uchida M, Nonaka M, Mineharu Y, Kitamura Y, Yamashita S, Yamauchi T, Miyake Y, Deguchi S, Beppu T, Tamura K, Koizumi S, Hirose Y, Asano K, Hiruta R, Kinoshita M, Miyake K, Nakayama N, Inoue A, Ono T, Sasaki T, Akiyama Y, Fukami S, Yoshino A, Kawanishi Y, Asanome T, Yamaguchi T, Takahashi M, Yamasaki F, Arakawa Y, Narita Y : Impact of tumor-treating fields on the survival of Japanese patients with newly diagnosed glioblastoma: A multicenter, retrospective cohort study. Neurooncol Adv. 2024 Nov 28;6(1):vdae176. doi: 10.1093/noajnl/vdae176. eCollection 2024 Jan-Dec. 10. Satomi K, Shibayama T, Hibiya T, Hayashi A, Nagahama K, Kato K, Nikai Y, Matsushita Y, Gomyo M, Yamagishi Y, Sasaki N, Saito K, Kobayashi K, Takeda A, Fujimoto S, Matsuo T, Takai K, Komori T, Tsuchiya K, Nagane M, Ichimura K, Shibahara J.: MYB::QKI fusion-positive diffuse glioma of the cerebellum: A case report. Neuropathology. 2024 Nov 21. doi: 10.1111/neup.13016. 11. Hibiya T, Nagahama K, Matsumoto Y, Saito K, Sasaki N, Kobayashi K, Otsu A, Shimasaki T, Takeuchi K, Shiokawa Y, Nagane M, Shibahara J. Epstein-Barr virus-positive monoclonal lymphoplasmacytic proliferation associated with neurosyphilis in an immunocompetent patient: A case report. Neuropathology. 2024 Apr;44(2):104-108. doi: 10.1111/neup.12934. Epub 2023 Jul 9. 12. 齊藤邦昭、Stealth™Tractography Clinical Report トラクトグラフィ抽出方法とCSD法の有用性、日本メドトロニック、2024年 13. 齊藤邦昭、シミュレーションで学ぶ脳腫瘍手術のピットフォールと失敗回避方法~神経膠腫~、医療用3Dワークステーションで学ぶ脳神経外科手術戦略シミュレーション、中外医学社、2024年 14. Kaishi Satomi, Kuniaki Saito, et al. The role of nonlinear dimension reduction of genome-wide DNA methylome in integrated diagnosis: A case study of glioblastoma, IDH-wildtype Pathol Int. 2023 Oct;73(10):523-526. 15. 齊藤邦昭、CT：脳実質の動静脈系の評価、日本臨牀第81巻増刊号9 臨床脳腫瘍学、p191-197、2023年 16. Yuki Yamagishi, Nobuyoshi Sasaki, Yoshiko Nakano, Yuko Matushita, Takaki Omura, Saki Shimizu, Kuniaki Saito et al. Liquid biopsy of cerebrospinal fluid for MYD88 L265P mutation is useful for diagnosis of central nervous system lymphoma, Cancer Sci. 2021 Nov;112(11):4702-4710. 17. 齊藤邦昭、グリオーマ摘出における各摘出器具の利点や使い分け 「CUSA派」の立場から. 脳神経外科速報2021年増刊 メディカ出版、p241-245、2021年 18. Takahashi S, Takahashi M, Kinoshita M, Miyake M, Kawaguchi R, Shinojima N, Mukasa A, Saito K et al. Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities, 2021 Mar 19;13(6):1415 19. Kuniaki Saito, Glioma Surgery and Surgical Supporting Technology, No Shinkei Geka. 2021 May;49(3):536-548. 20. Reduced neoantigen expression revealed by longitudinal multiomics as a possible immune evasion mechanism in glioma. Nejo T, Matsushita H, Karasaki T, Nomura M, Saito K, Tanaka S, Takayanagi S, Hana T, Takahashi S, Kitagawa Y, Koike T, Kobayashi Y, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Narita Y, Nagane M, Ueki K, Nishikawa R, Aburatani H, Mukasa A, Saito N, Kakimi K.: Cancer Immunol Res. 2019 Jul;7(7):1148-1161 21. [Surgical Anatomy and Operative Technique for Insular Glioma]. Saito K.: No Shinkei Geka. 2019 Apr;47(4):405-418. 22. DNA demethylation is associated with malignant progression of lower-grade gliomas. Nomura M, Saito K, Aihara K, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Takayanagi S, Otani R, Nejo T, Hana T, Takahashi S, Kitagawa Y, Omata M, Higuchi F, Nakamura T, Muragaki Y, Narita Y, Nagane M, Nishikawa R, Ueki K, Saito N, Aburatani H, Mukasa A.: Sci Rep. 2019 Feb 13;9(1):1903 23. Hepatosplenic γδ T Cell Lymphoma Involving the Brain. Iijima S, Chiba T, Maruyama K, Saito K, Kobayashi K, Yamagishi Y, Shibahara J, Takayama N, Shiokawa Y, Nagane M.: World Neurosurg. 2018 Oct;118:139-142. 24. Smart Glasses for Neurosurgical Navigation by Augmented Reality. Maruyama K, Watanabe E, Kin T, Saito K, Kumakiri A, Noguchi A, Nagane M, Shiokawa Y.: Oper Neurosurg (Hagerstown). 2018 Nov 1;15(5):551-556. 25. Genetic and epigenetic stability of oligodendrogliomas at recurrence. Aihara K, Mukasa A, Nagae G, Nomura M, Yamamoto S, Ueda H, Tatsuno K, Shibahara J, Takahashi M, Momose T, Tanaka S, Takayanagi S, Yanagisawa S, Nejo T, Takahashi S, Omata M, Otani R, Saito K, Narita Y, Nagane M, Nishikawa R, Ueki K, Aburatani H, Saito N.: Acta Neuropathol Commun. 2017 Mar 7;5(1):18. 26. Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: a case report and review of the literature. Saito K, Mukasa A, Yanagisawa S, Tanaka S, Takai K, Shibahara J, Ikegami M, Nakao Y, Takeshita K, Matsutani M, Saito N: J Neurosurg Spine, 2017 Mar;26(3):319-324 27. Genetic and epigenetic stability of oligodendrogiomas at recurrence. Aihara K, Mukasa A, Nagae G, Nomura M, Yamamoto S, Ueda H, Tatsuno K, Shibahara J, Takahashi M, Momose T, Tanaka S, Takayanagi S, Yanagisawa S, Nejo T, Takahashi S, Omata M, Otani R, Saito K, Narita Y, Nagane M, Nishikawa R, Ueki K, Aburatani H, Saito N: Acta Neuropathol Commun.2017 Mar7;5(1):18 28. Black hairy tongue after chemotherapy for malignant brain tumors. Yamagishi Y, Maruyama K, Kobayashi K, Kume S, Sasaki N, Yokoya S, Saito K, Shiokawa Y, Nagane M; Acta Neurochir. 2017 Jan;159(1)169-172 29. 10qLOH. 齊藤邦昭; 脳腫瘍学―基礎研究と臨床研究の進歩―2016 Sep: 126-131. 30. 脈絡叢腫瘍. 齊藤邦昭、永根基雄; 脳神経外科診療プラクティス グリオーマ治療のDecision Making. 2016: 64-68. 31. A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas. Arita H, Saito K(53人中12番目), Ichimura K: Acta Neuropathol Commun. 2016 Aug 8;4(1):79 32. Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study. Saito K, Mukasa A, Narita Y, Tabei Y, Shinoura N, Shibui S, Saito N: Neurol Med Chir 54(4): 272-9, 2014. 33. Frequent H3F3A K27M Mutations in Thalamic Gliomas of Young Adult Patients. Aihara K, Mukasa A, Gotoh K, Nagae G, Tsuji S, Saito K, Takayanagi S, Tatuno K, Yamamoto S, Narita Y, Shibui S, Aburatani H, Saito N: Neuro-Oncology 16(1): 140-6, 2014 34. H3F3A K27M mutations in thalamic gliomas from young adult patients. Aihara K, Mukasa A, Gotoh K, Saito K, Nagae G, Tsuji S, Tatsuno K, Yamamoto S, Takayanagi S, Narita Y, Shibui S, Aburatani H, Saito N: Neuro Oncol. 16(1): 140-6, 2014 35. Corticospinal tract-sparing intensity-modulated radiotherapy treatment planning. Igaki H, Sakumi A, Mukasa A, Saito K, Kunimatsu A, Masutani Y, Hanakita S, Ino K, Haga A, Nakagawa K, Ohtomo K: Rep Pract Oncol Radiother. 19(5): 310-6, 2014 36. Ptosis as partial oculomotor nerve palsy due to compression by infundibular dilatation of posterior communicating artery, visualized with three-dimensional computer graphics: case report. Fukushima Y, Imai H, Yoshino M, Kin T, Takasago M, Saito K, Nakatomi H, Saito N: Neurol Med Chir 54(3): 214-8, 2014 37. Stereotactic Radiosurgery for intracranial Gliomas. Tanaka S, Shin M, Mukasa A, Hanakita S, Saito K, Koga T, Saito N: Neurosurg Clin N Am. 2013 Oct;24(4): 605-612. 38. 高齢者神経膠腫の治療. 齊藤邦昭. Clinical Neuroscience 2013Oct ;31(10):1198-1200 39. Significance of IDH mutation varies with tumor histology, grade, and genetics in Japanese glioma patients. Mukasa A, Takayanagi S, Saito K, Shibahara J, Tabei Y, Furuya K, Ide T, Narita Y, Nishikawa R, Ueki K, Saito N. Cancer Sci. 103(3): 587-92, 2012. 40. 脳腫瘍の治療―外科療法―. 斉藤延人、齊藤邦昭、花北俊哉. 癌診療指針のための病理診断プラクティス 脳腫瘍 2012: 52-63. 41. Advantages and disadvantages of awake surgery for brain tumours in the primary motor cortex : institutional experience and review of literature. Shinoura N, Yamada R, Tabei Y, Saito K, Suzuki Y, Yagi K. Br J Neurosurg. 25(2):218-24, 2011. 42. Combined damage to the right hemispheric hand area in the primary motor and sensory area plays a critical role in motor hemineglect. Shinoura N, Yoshida M, Yamada R, Tabei Y, Saito K, Suzuki Y, Yagi K. Eur Neurol. 63(1):17-23, 2010. 43. Deficits in the left inferior longitudinal fasciculus results in impairments in object naming. Shinoura N, Suzuki Y, Tsukada M, Yoshida M, Yamada R, Tabei Y, Saito K, Koizumi T, Yagi K. Neurocase. 16(2): 135-9, 2010. 44. Relationships between brain tumor and optic tract or calcarine fissure are involved in visual field deficits after surgery for brain tumor. Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K, Yagi K. Acta Neurochir (Wien). 152(4): 637-42, 2010. 45. Long-term survival following metachronous intratumoral hemorrhage in an HIV-infected patient with lung cancer. Okuma Y, Hosomi Y, Takagi Y, Miyamoto S, Shimokawa T, Iguchi M, Okamura T, Saito K, Shibuya M. K. Int J Clin Oncol. 15(5): 515-8, 2010. 46. Awake surgery with continuous motor testing for resection of brain tumors in the primary motor area. Shinoura N, Yoshida M, Yamada R, Tabei Y, Saito K, Suzuki Y, Takayama Y, Yagi K. J Clin Neurosci. 2009 Feb;16(2):188-94. 47. Precentral knob corresponds to the primary motor and premotor area. Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K, Yagi K. Can J Neurol Sci. 2009 Mar;36(2):227-33. 48. Assessment of the corona radiata sensory tract using awake surgery and tractography. Shinoura N, Suzuki Y, Yoshida M, Yamada R, Tabei Y, Saito K, Yagi K. J Clin Neurosci. 2009 Jun;16(6):764-70. 49. Marked and rapid recovery of motor strength in promoter area compared with primary motor area in surgery for brain tumors. Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K, Yagi K. Br J Neurosurg. 2009 Jun;23(3):309-14. 50. [Awake surgery plays a role in neurosurgery and neuroscience].Shinoura N, Yamada R, Tabei Y, Saito K, Suzuki Y, Yoshida M, Takahashi M, Nakamura O, Takayama Y, Yagi K: Brain Nerve 60:941-947, 2008. 51. Mirror therapy activates outside of cerebellum and ipsilateral M1. Shinoura N, Suzuki Y, Watanabe Y, Yamada R, Tabei Y, Saito K, Yagi K: NeuroRehabilitation 23:245-252, 2008. 52. [Temozolomide: Temodal]. Shinoura N, Yamada R, Tabei Y, Saito K, Nakamura O, Takahashi M: Gan To Kagaku Ryoho 35:543-547, 2008. 53. Continuous intrathecal treatment with methotrexate via subcutaneous port: implication for leptomeningeal dissemination of malignant tumors. Shinoura N, Tabei Y, Yamada R, Saito K, Takahashi M: J Neurooncol 87:309-316, 2008. 54. Impairment of inferior longitudinal fasciculus plays a role in visual memory disturbance. Shinoura N, Suzuki Y, Tsukada M, Katsuki S, Yamada R, Tabei Y, Saito K, Yagi K: Neurocase 13:127-130, 2007. 55. Spinal intramedullary ependymal cyst: a case report and review of the literature. Saito K, Morita A, Shibahara J, Kirino T: Acta Neurochir(Wien) 147:443-6, 2005 研究費獲得歴： ・令和6年度科学研究費補助金(基盤C)：グリオーマのliquid biopsyによるメチル化網羅的解析とprecision medicineへの応用 ・令和3年度科学研究費補助金(基盤C)：膠芽腫のメチル化プロファイルに応じた治療効果予測とエピゲノム個別化療法の創出 ・平成29年度科学研究費補助金(基盤C)：グリオーマ血清/髄液中DNA高感度解析によるliquid biopsyの確立 ・平成26年度科学研究費補助金(基盤C)：神経膠腫およびその幹細胞のエピジェネティクス統合解析と新規診断、治療への応用 ・平成24年度科学研究費補助金(若手B)：悪性神経膠腫におけるエピジェネティックマーカーの探索と個別化治療への応用 ・平成22年度科学研究費補助金(若手B)：膠芽腫およびその腫瘍幹細胞のepigenetic profileに応じた個別化療法の基礎研究 | |
| 所属学会 |
日本脳神経外科学会 日本脳神経外科コングレス 日本脳腫瘍学会 (事務局長) 日本脳腫瘍の外科学会（評議員） 日本癌学会 日本癌治療学会 日本神経内視鏡学会 日本分子脳神経外科学会 日本脳神経CI学会 ニューロオンコロジィの会 Society for Neuro-Oncology Asian Society for Neuro-Oncology | |
| 学外活動 | 日本脳腫瘍学会事務局長 | |